Experimental Studies on Germinal Localization (1904), by Edmund B. Wilson
نویسندگان
چکیده
At the turn of the twentieth century, Edmund B. Wilson performed experiments to show where germinal matter was located in molluscs. At Columbia University [4] in New York City, New York, Wilson studied what causes cells to differentiate during development. In 1904 he conducted his experiments on molluscs, and he modified the theory about the location of germinal matter in the succeeding years. Wilson and others modified the theory of germinal localization to accommodate results that showed the significance of chromosomes in development and heredity.
منابع مشابه
Local accumulation of Feulgen-positive granules in the egg cortex of Dentalium dentale L.
A special feature of eggs of several species of annelids and molluscs is the formation of a polar lobe at stage-specific intervals during the cleavage phase. In the scaphopod Dentalium, a polar lobe develops at the first, the second and the third cleavage (Wilson, 1904). The cytoplasm set apart in the polar lobes is ultimately confined to the D blastomere and its derivative cells. Wilson observ...
متن کاملBiology of germinal centers in lymphoid tissue.
Germinal centers in lymphoid tissue are the sites of generation of memory B cells undergoing isotype switching and somatic mutation in their Ig genes. Their formation cannot be induced by stimuli other than immunogenic ones. It seems likely that in the function and possibly also in the formation of germinal centers, one important factor is the localization of immune complexes with fixed complem...
متن کاملEstimation of Velocity and Detonation Pressure of some High Energy Compounds using Kamlet Method based on Kistiakowski-Wilson Rules
In the present study, the heat of detonation of high energy compounds with CaHbNcOd formula was obtained according to Kistiakowski-Wilson rules. Comparison of these results with experimental date, group additivity method and Kamlet method shows that the values of heat detonation based on the Kistiakowski-Wilson rules are more accurate. In the following, the values of detonation velocity and de...
متن کاملCellular Localization of Immunoglobulins with Different Allotypic Specificities in Rabbit Lymphoid Tissues
The cellular localization of allotypes in rabbit lymphoid tissues has been studied by immunofluorescence. In heterozygous animals the double staining for two allotypes controlled by allelic genes (A1 and A2; A4 and A5; A4 and A6) has shown the existence of two populations of plasma cells, one containing one allotype and the other the alternative one. The localization in different cells of immun...
متن کاملIn situ studies of the primary immune response to (4-hydroxy-3- nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers
In the genetically restricted response that follows immunization with (4-hydroxy-3-nitrophenyl)acetyl coupled to protein carriers, two distinct populations of B cells are observed in the spleens of C57BL/6 mice. By 48 h postimmunization, foci of antigen-binding B cells appear along the periphery of the periarteriolar lymphoid sheaths. These foci expand to contain large numbers of antibody-formi...
متن کامل